Recent Entries

  • Tactical Gear - Be Prepared Always

    People may have this perception that you can only be in the military in order to get a chance to use any military gear. Actually, there is quite a range of tactical military gear that is available which one will definitely find useful some way or another. Here are a few to conside...
  • Survival Gear - Fitting In

    Going to this concert requires some survival tactics, and if you don't have them, it is better you get equipped now. You need to be prepared in advance before you attend this concert. There are going to be lots of bands, and lots of fans. It's going to be hot, and it can get wet. Are you prepared ...
  • Where to Find Discount Stainless Steel Kitchen Sinks

    Kitchen sinks are not cheap. That's why it's so important to choose the type that fits your kitchen design and purpose. One of the popular types of sinks used today is the stainless steel kitchen sink - it doesn't come cheap but if you know where to look, you'll surely get it for a low price. Barga...
  • Five Fingers Shoes Are The Hottest Shoe Trend Now

    Just what are the five fingers shoes? The shoes with five fingers are exactly what they sound like - footwear with specific toe openings for every one of the five toes. They provide quite a few great advantages over classical sport shoes. The obvious benefit is the exceptional grip on any sur...
  • Finding Wholesale Shoes

    If you are looking for wholesale shoes, then you already know that quality makes a big difference to the asking price of the shoes. You probably already know that brands also make a difference. It is important that you consider these two things if you are trying to buy shoes wholesale and then res...
  • Protein structure illuminates how viruses take over cells

    Using cutting-edge imaging technology, Salk Institute and Harvard Medical School researchers have determined the structure of a protein complex that lets viruses similar to the human immunodeficiency virus (HIV) establish permanent infections within their hosts. Contrary to previous assumptions, ...
  • Proteins critical to wound healing identified

    Mice missing two important proteins of the vascular system develop normally and appear healthy in adulthood, as long as they don't become injured. If they do, their wounds don't heal properly, a new study shows. The research, at Washington University School of Medicine in St. Louis, may have impl...
  • Advantages of prokaryotic expression system

    We all know that there are many ways of protein Expression, such as mammalian cell Expression system, insect cell Expression system, This time, I would like to introduce the expression of bacillus . Bacillus expression is a gram-positive bacterium widely used in industrial production. Differen...
  • Principles to be followed in vaccine preclinical assay (Part Tw

    Vaccine production process research (1) Establishing a bacterial strain bank Establish a three-level seed bank. The genetic stability of the seed bank was analyzed to determine the number of times the seed bank could be passaged. Production of bacterial strains, cells and process technologies...
  • A brief talk on the GLP vaccine ADME

    Hepatitis B is a life-threatening liver infection caused by hepatitis B virus. In 2015, about 887,000 people worldwide suffered from post-hepatitis B cirrhosis and liver cancer. Since 1987, Beijing has been vaccinating newborns with hepatitis B vaccine. In 2002, hepatitis B vaccine assessment h...
  • Biomarkers: Our Liver's Guardian

    Liver is an organ that gives priority to metabolic function, playing the role that go oxidizing, store liver candy, secretion sex protein is synthesized etc. It is the largest organ in the internal organs of the human body, located in the abdomen of the human body, under the right diaphragm, in fron...
  • A brief talk on the Xanthohumol

    A special substance in hops called Xanthohumol has attracted more and more people's attention. It belongs to isopentene flavonoids (Xantho-humol, referred to as Xn). Scientists have shown that Xanthohumol has obvious anti-cancer effects. The Xanthohumol is a kind of biocatalyst, which has an a...
  • A brief talk on the maltase enzyme

    maltase enzyme was originally the name used for enzymes that hydrolyze maltose to 2-molecule glucose, but is now generally used as an alias for alpha-glucosidase that binds to various glycosyls. Maltose maltose refers to 2 molecules D- glucose alpha -1, 4 bond two sugar. According to the chemic...
  • Aldehyde dehydrogenase: an overview

    Acetaldehyde dehydrogenase, abbreviated as ALDH, a kind of aldehyde dehydrogenase, responsible for catalyzing the oxidation of acetaldehyde to acetic acid. The alcohol dehydrogenase in the liver is responsible for the oxidation of ethanol (the component of wine) to acetaldehyde. The aldehyde is furt...
  • Introduction of Alzheimer disease

    What is Alzheimer disease?   Alzheimer disease (AD), is a degenerative disease of the central nervous system. Its early clinical manifestations are mainly the impairment of memory and the decline of self-care ability, which eventually leads to cognitive impairment and loss, neurobehavioral ab...
  • A brief talk on the phage panning

    Gene cloning is the basis of gene engineering and molecular biology research. With the rapid development of biotechnology in the 21st century, gene cloning technology is more and more widely used. Since Hofstetter et al. first successfully constructed the cDNA library by hybridizing plasmids in 1976...
  • Nuclear transfer of mitochondrial DNA in colon and rectal cance

    Patients with colon and rectal cancer have somatic insertions of mitochondrial DNA into the nuclear genomes of the cancer cells, University of Alabama at Birmingham researchers report in the journal Genome Medicine. This study provides the novel role for mitochondria inducing genomic instabi...
  • Vaccine R&D to Vaccination (Part Two)

    To be continued from Part One: Vaccine preclinical assay (1) The human clinical trial is divided into four phases: namely, phase I, phase II, phase III and phase IV. The phase I focuses on safety and the subjects should be healthy, usually adults. The purpose of the Phase II assay is to obse...
  • Introduction of Fab Antibody

    What is Fab fragment?   Fab fragments, also known as antigen-binding fragments, are regions in the structure of antibodies that can bind to antigens. Fab fragment consists of a complete VH and CH1 domains of light and heavy chains. Both light chain and heavy chain have a constant region and a...
  • Introduction to Single Molecule Sequencing

    Single molecule sequencing A DNA strand polymerase is used to synthesize a DNA strand complementary to the template, and the position of the template and the nucleotide&nbs...
  • A Detailed Introduction of MAP Kinase Signaling Pathway

    MAPK is an important transmitter of signals from the cell surface to the interior of the nucleus. Mitogen-activated protein kinase (MAPK) is a group of serine-threonine that can be activated by different extracellular stimuli such as cytokines, neurotransmitters, hormones, cellular stress and cell a...
  • How much do you know these three signaling pathway?

    Do you know CD40/CD40L Signaling Pathway? CD40L belongs to tumor necrosis factor,TNF. Type II transmembrane proteins in the superfamily are expressed on the surface of activated CD 4T cells, B cells and cancer cells. The process of CD40/CD40L signaling pathway is that CD40L receptor mol...
  • How much do you know about Protein G?

    Protein G is a cell wall protein isolated from streptococcus G. Streptococcus protein G is a cell wall protein on the surface of Streptococcus streptococcus, which consists of nearly 600 amino acids. The N-terminal part is albumin binding domain, and the C-terminal part is IgG binding domain and cel...