Recent Entries

  • Are Portable Sinks Useful in Daycare Centres?

    Benefits There are some benefits that the usage of a portable handwashing sink in a daycare centre brings. Even though these are just humble reasons, they are still great reasons. The thing most people would agree that these portable sinks used in daycare centres are beneficial to the children. T...
  • LED Grow Lights - The Environmental Choice

    Plants need light. Hydroponic plants are no exception. LED grow lights provide the full spectrum of light that plants need for photosynthesis. Without this, the plants will die. Other lighting methods have been used in the past, but these have not produced the quality of lighting that the LED grow...
  • Tactical Backpacks - 3 Required Features

    If you are the adventurous type and happen to be looking for some backpacks, you could check out the available range of tactical backpacks as they are known to be of top quality and value for money. Here are 3 required features to look out for. Lots Of Space The idea of people getting ho...
  • Five Fingers Shoes Are The Hottest Shoe Trend Now

    Just what are the five fingers shoes? The shoes with five fingers are exactly what they sound like - footwear with specific toe openings for every one of the five toes. They provide quite a few great advantages over classical sport shoes. The obvious benefit is the exceptional grip on any sur...
  • Tactical Equipment For Everyone

    It's hardly surprising that terms such as tactical equipment or tactical gear make people think about things like multicam tactical vests with ammunition pouches worn by soldiers and SWAT team members. But just because something was designed with these users in mind doesn't mean those products are n...
  • The Military Combat Boots

    The soldiers in military, navy, air force and other armed forces always face situations that require more running, walking, standing, and even jumping. The soldiers always face more rugged conditions and physical activities that can easily wear out their shoes and even their feet. It is for these re...
  • The Differences Between Manual and Automatic Cat Litter Boxes

    There are two types of cat litter boxes: manual and automatic. These two categories refer to different cleaning methods. Automatic boxes are, as the name suggests, self-cleaning, whereas manual ones require user labor. Automatic boxes are often more expensive than manual boxes but require far less u...
  • 5 Tips to Save Time When You Litter Train a Cat to Use Automati

    An automatic cat litter offers great convenience to cat owners. It will automatically scoop up the used litter after your cat uses the litter box. A good point is the wide range of modern designs available. There are many different sizes of automatic cat litter boxes. Some are open, while other...
  • Something about Amyloid Beta-Protein

    There are some antibodies to amyloid beta-protein: Crenezumab Recombinant monoclonal antibody to Aβ. Crenezumab is a humanized monoclonal antibody against human 1-40 and 1-42 Beta amyloid, which is being investigated as a treatment of Alzheimer's disease.   Gantenerumab ...
  • Introduction to Epithelial Growth Factor Receptor

    There are some antibodies: 1. Nimotuzumab Anti-EGFR antibody (Nimotuzumab) is a humanized antibody of IgG that binds to an EGFR.       Necitumumab Necitumumab (proposed INN) is a monoclonal antibody and an antineoplastic, which binds to the epidermal growth...
  • A Guide for Selection of Delivery Vectors for Cancer Vaccine (p

    Bacterial Vectors 2.1 Listeria Monocytogenes Listeria monocytogenes (LM) is a Gram-positive bacterium, in the division Firmicutes, named after Joseph Lister. It is the species of pathogenic bacteria that causes the infection listeriosis. It is a facultative anaerobic bacterium, capable o...
  • A Review of Research Progress in Diabody Drugs

    Antibody drugs have flourished in the past 20 years. At present, there are varieties of antibody drugs marketed globally, and their therapeutic fields have gradually expanded from traditional cancers and autoimmune diseases to anti-infective and metabolic diseases. In 2013, there were 6 antibody dru...
  • What is protein mutagenesis

    Protein mutagenesis refers to the introduction of desired changes (usually in a favorable direction), including addition, deletion, and point mutations, into the target DNA fragment (either genome or plasmid) by means of polymerase chain reaction (PCR) and other methods. Site-directed mutation can r...
  • The Effective Hand of Wound Healing: PDGF

    Platelet derived growth factor (PDGF) is a basic protein stored in platelet alpha particle, and is a low molecular weight cytokinin. It can stimulate a variety of cells, such as fibroblasts which are stagnant in G0/G1 phase, glial cells and smooth muscle cells, to enter the cycle of proliferati...
  • How You Can Invest in Wholesale Clothes

    Once you purchase wholesale clothing, you really conserve a bundle of common retail rates. Consumers largely buy garments wholesale to ensure that they are able to market them once again in list prices and at some point make a earnings. Obtaining wholesale prices signifies you need to acquire them ...
  • Suggestions for therapeutic antibody drug R&D companies

    Therapeutic antibodies have a broad development potential. According to relevant data, the market for therapeutic antibody drugs in the world can reach 320 billion US dollars by 2021. The therapeutic antibody drugs have huge market possibility. For innovative antibody research organizations and de...
  • Data analysis research methods

    Univariate analysis is the simplest form of data analysis in which the data being analyzed contains only one variable. Because it is a single variable, it does not deal with causes or relationships. Corresponding to univariate analysis is multivariate analysis, in addition, there are a series o...
  • Electroporation---an Efficient Biotransformation Method

    Abstract: Before introducing electroporation, an important concept-gene library is introduced. A gene library is a recombinant population obtained by fragmenting and completely cloning a certain genome, and constructing a highly abundant gene library greatly increases the effectiveness and ta...
  • Introduction to C3

    Firstly, let us know an antibody—— recombinant anti-C3 antibody Recombinant Human Antibody (S77) is capable of binding to C3, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-C3 mAb and CH1-3 region of human IgG and a light chain (LC...
  • Classification and application of Fatty Acid

    Introduction Fatty acid is a kind of carboxylic acid compound also called free fatty acid when it exists alone. Three long chain fatty acids and glycerol form three acid glyceride (Triacylglycerols) as the main components of the fat. The lower fatty acids are colorless liquids with p...
  • Approaching 3d cell culture

    The three-dimensional cell culture is mainly based on the 3d cell culture scaffold model, which can better simulate the growth environment of the cells in the body.   Definition: Three-dimensional cell culture technology, ie 3d cell culture techniques, means that there will be...
  • How much do you know about traditional cell culture technology?

    Cell culture is also called cell cloning technology, also known as cell culture technology. Cell culture is an indispensable process for whole bioengineering technology and bioclone technology. Cell culture itself is a large-scale cloning of cells. Cells can be cultured from one cell to a simple sin...
  • Insulin receptor and gene expression

    The discovery of insulin in the 1920s marked the breakthrough in the almost 3,500-year-long mystery of diabetes, a disease first described in ancient Egyptian papyruses. Until its discovery, physicians struggled to explain how symptoms such as sugary urine, constant thirst and frequent urination cou...
  • Characteristics of peptide nucleic acids

    Peptide nucleic acids, a class of DNA analogs that replace the sugar phosphate backbone with a polypeptide backbone, are a new nucleic acid sequence-specific reagent that Danish organic chemist Ole Buchardt and biochemist Peter Nielsen began to study in the 1980s. It is a third-generation antisens...
  • What is Polygalic acid?

    Polygalic acid has a strong sputum effect; it has an inhibitory effect on cyclic adenosine phosphate diterpene enzyme; it can enhance the body's physical strength and intelligence; it has a strong hemolysis effect and has an inhibitory effect on aldosterone reductase. In addition, there are ant...
  • Introduction to Neuromyelitis optica (NMO)

    Neuromyelitis optica (NMO) is an acute or subacute demyelinating lesion that occurs simultaneously or sequentially in the optic nerve and spinal cord. The disease was first described by Devic (1894), whose clinical features were monocular or binocular blindness with acute or subacute onset, with t...
  • Progress for Autoimmune Disease Vaccine (Part Two)

    2.3 Type 1 diabetes Type 1 diabetes is a T cell-mediated autoimmune disease against islets (the autoimmune disease characterized by monocyte infiltration in islet cells and production of islets (autoantibodies of cells, activated autoreactive T cells versus islets) (The cell attacks, resulting...
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  • The New Weapon of Laboratory Medicine: In Vitro Diagnostics

    In vitro diagnosis refers to the products and services that acquire clinical diagnostic information through testing human body samples (blood, body fluids, tissues, etc.) outside the human body, so as to judge diseases or bodily functions. In other words, in vitro diagnosis (IVD) refers to the ...
  • The complete guide to CAR T-cell therapy

    What is CAR T-cell therapy? CAR T refers to chimeric antigen receptor T cell. CAR T-cell therapy is a type of immunotherapy that uses specially altered T cells —derived from our immune system — to fight cancers. Usually during the process, a sample of a patient's T cells are c...
  • Finding Wholesale Shoes

    If you are looking for wholesale shoes, then you already know that quality makes a big difference to the asking price of the shoes. You probably already know that brands also make a difference. It is important that you consider these two things if you are trying to buy shoes wholesale and then res...
  • Protein structure illuminates how viruses take over cells

    Using cutting-edge imaging technology, Salk Institute and Harvard Medical School researchers have determined the structure of a protein complex that lets viruses similar to the human immunodeficiency virus (HIV) establish permanent infections within their hosts. Contrary to previous assumptions, ...
  • Proteins critical to wound healing identified

    Mice missing two important proteins of the vascular system develop normally and appear healthy in adulthood, as long as they don't become injured. If they do, their wounds don't heal properly, a new study shows. The research, at Washington University School of Medicine in St. Louis, may have impl...
  • Advantages of prokaryotic expression system

    We all know that there are many ways of protein Expression, such as mammalian cell Expression system, insect cell Expression system, This time, I would like to introduce the expression of bacillus . Bacillus expression is a gram-positive bacterium widely used in industrial production. Differen...
  • Principles to be followed in vaccine preclinical assay (Part Tw

    Vaccine production process research (1) Establishing a bacterial strain bank Establish a three-level seed bank. The genetic stability of the seed bank was analyzed to determine the number of times the seed bank could be passaged. Production of bacterial strains, cells and process technologies...
  • A brief talk on the GLP vaccine ADME

    Hepatitis B is a life-threatening liver infection caused by hepatitis B virus. In 2015, about 887,000 people worldwide suffered from post-hepatitis B cirrhosis and liver cancer. Since 1987, Beijing has been vaccinating newborns with hepatitis B vaccine. In 2002, hepatitis B vaccine assessment h...
  • Biomarkers: Our Liver's Guardian

    Liver is an organ that gives priority to metabolic function, playing the role that go oxidizing, store liver candy, secretion sex protein is synthesized etc. It is the largest organ in the internal organs of the human body, located in the abdomen of the human body, under the right diaphragm, in fron...
  • Slow-binding inhibition of cholinesterases: Pharmacological, to

    Reversible inhibition of enzyme, an activity in which the inhibiting molecular entity (often a small chemical called ligand or inhibitor) can associate and dissociate from the protein's binding site, is a very fast process. As for enzyme-substrate interaction, enzyme-inhibitor equilibrium establishe...
  • A brief talk on the Xanthohumol

    A special substance in hops called Xanthohumol has attracted more and more people's attention. It belongs to isopentene flavonoids (Xantho-humol, referred to as Xn). Scientists have shown that Xanthohumol has obvious anti-cancer effects. The Xanthohumol is a kind of biocatalyst, which has an a...
  • A brief talk on the maltase enzyme

    maltase enzyme was originally the name used for enzymes that hydrolyze maltose to 2-molecule glucose, but is now generally used as an alias for alpha-glucosidase that binds to various glycosyls. Maltose maltose refers to 2 molecules D- glucose alpha -1, 4 bond two sugar. According to the chemic...
  • Aldehyde dehydrogenase: an overview

    Acetaldehyde dehydrogenase, abbreviated as ALDH, a kind of aldehyde dehydrogenase, responsible for catalyzing the oxidation of acetaldehyde to acetic acid. The alcohol dehydrogenase in the liver is responsible for the oxidation of ethanol (the component of wine) to acetaldehyde. The aldehyde is furt...
  • Introduction of Alzheimer disease

    What is Alzheimer disease?   Alzheimer disease (AD), is a degenerative disease of the central nervous system. Its early clinical manifestations are mainly the impairment of memory and the decline of self-care ability, which eventually leads to cognitive impairment and loss, neurobehavioral ab...
  • A brief talk on the phage panning

    Gene cloning is the basis of gene engineering and molecular biology research. With the rapid development of biotechnology in the 21st century, gene cloning technology is more and more widely used. Since Hofstetter et al. first successfully constructed the cDNA library by hybridizing plasmids in 1976...
  • Nuclear transfer of mitochondrial DNA in colon and rectal cance

    Patients with colon and rectal cancer have somatic insertions of mitochondrial DNA into the nuclear genomes of the cancer cells, University of Alabama at Birmingham researchers report in the journal Genome Medicine. This study provides the novel role for mitochondria inducing genomic instabi...
  • Vaccine R&D to Vaccination (Part Two)

    To be continued from Part One: Vaccine preclinical assay (1) The human clinical trial is divided into four phases: namely, phase I, phase II, phase III and phase IV. The phase I focuses on safety and the subjects should be healthy, usually adults. The purpose of the Phase II assay is to obse...
  • Introduction of Fab Antibody

    What is Fab fragment?   Fab fragments, also known as antigen-binding fragments, are regions in the structure of antibodies that can bind to antigens. Fab fragment consists of a complete VH and CH1 domains of light and heavy chains. Both light chain and heavy chain have a constant region and a...
  • Introduction to Single Molecule Sequencing

    Single molecule sequencing A DNA strand polymerase is used to synthesize a DNA strand complementary to the template, and the position of the template and the nucleotide&nbs...
  • A Detailed Introduction of MAP Kinase Signaling Pathway

    MAPK is an important transmitter of signals from the cell surface to the interior of the nucleus. Mitogen-activated protein kinase (MAPK) is a group of serine-threonine that can be activated by different extracellular stimuli such as cytokines, neurotransmitters, hormones, cellular stress and cell a...
  • How much do you know these three signaling pathway?

    Do you know CD40/CD40L Signaling Pathway? CD40L belongs to tumor necrosis factor,TNF. Type II transmembrane proteins in the superfamily are expressed on the surface of activated CD 4T cells, B cells and cancer cells. The process of CD40/CD40L signaling pathway is that CD40L receptor mol...
  • How much do you know about Protein G?

    Protein G is a cell wall protein isolated from streptococcus G. Streptococcus protein G is a cell wall protein on the surface of Streptococcus streptococcus, which consists of nearly 600 amino acids. The N-terminal part is albumin binding domain, and the C-terminal part is IgG binding domain and cel...
  • The Important Role of Diabody

    Abstract: The study of diabody began after the birth of monoclonal antibody technology in the 1980s. A bispecific antibody is a non-native antibody that has different specificities for the two arms that bind to the antigen. The construction of diabody is usually carried out using biological m...